iPTMnet Report for O00217 (NDUFS8)
Protein Information
UniProt AC / UniProt ID | O00217 / NDUS8_HUMAN |
Protein Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial precursor |
Gene Name | Name: NDUFS8 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O00217 |
PRO Name | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (human) |
Definition | An NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial that is encoded in the genome of human. |
Short Label | hNDUFS8 |
Category | organism-gene |
O00217 (NDUFS8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y38 | Phosphorylation | score1 | PhosphoSitePlus | |||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
T52 | Phosphorylation | score1 | PhosphoSitePlus | |||
S73 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
R96 | Methylation | score1 | PhosphoSitePlus | |||
R133 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S73 | G73 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R133 | G133 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R133 | K133 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |