iPTMnet Report for O00214 (LGALS8)
Protein Information
| UniProt AC / UniProt ID | O00214 / LEG8_HUMAN |
| Protein Name | Galectin-8 |
| Gene Name | Name: LGALS8 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00214 |
| PRO Name | galectin-8 (human) |
| Definition | A galectin-8 that is encoded in the genome of human. |
| Short Label | hLGALS8 |
| Category | organism-gene |
O00214 (LGALS8) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K57 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T200 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K212 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K291 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T180 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K193 | Methylation | score1 | PhosphoSitePlus | |||
| K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K204 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S55 | G55 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
| K85 | E85 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T180 | M180 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K193 | I193 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| K224 | Q224 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View