iPTMnet Report for O00192 (ARVCF)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00192 / ARVC_HUMAN
Protein Name Splicing regulator ARVCF
Gene Name Name: ARVCF
Organism Homo sapiens (Human)

PRO ID PR:O00192
DAG View
PRO Name splicing regulator ARVCF (human)
Definition A splicing regulator ARVCF that is encoded in the genome of human.
Short Label hARVCF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00192 (ARVCF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T102 Phosphorylation PhosphoSitePlus   UniProt 24275569
T104 Phosphorylation PhosphoSitePlus   UniProt 24275569
S105 Phosphorylation PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
T111 Phosphorylation PhosphoSitePlus
T177 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
Y259 Phosphorylation PhosphoSitePlus
T265 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y282 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus   UniProt 24275569
S335 Phosphorylation PhosphoSitePlus   UniProt 24275569
S343 Phosphorylation PhosphoSitePlus   UniProt 24275569
S345 Phosphorylation PhosphoSitePlus   UniProt 24275569
S348 Phosphorylation PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
R591 Methylation PhosphoSitePlus
Y592 Phosphorylation PhosphoSitePlus
S602 Phosphorylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus   UniProt 24275569
T642 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
K647 Ubiquitination PhosphoSitePlus
T838 Phosphorylation PhosphoSitePlus
K841 Acetylation PhosphoSitePlus
K860 Ubiquitination PhosphoSitePlus
S864 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S871 Phosphorylation PhosphoSitePlus   UniProt 19690332
T872 Phosphorylation PhosphoSitePlus   UniProt 19690332
K878 Ubiquitination PhosphoSitePlus
Y901 Phosphorylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus
T903 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S267 Phosphorylation HPRD 15345747, 19664994
S602 Phosphorylation HPRD 20068231
T642 Phosphorylation HPRD 18669648, 19664994, 19664995
S864 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S200 T200 Biomuta DOID:184 / bone cancer [ cosmic ]
T228 P228 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T322 M322 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S332 N332 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S345 T345 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S345 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T642 M642 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K841 R841 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T903 M903 Biomuta DOID:10534 / stomach cancer [ cosmic ]