Protein Information

Cytoscape View


UniProt AC / UniProt ID O00187 / MASP2_HUMAN
Protein Name Mannan-binding lectin serine protease 2 precursor
Gene Name Name: MASP2
Organism Homo sapiens (Human)

PRO ID PR:O00187
DAG View
PRO Name mannan-binding lectin serine protease 2 (human)
Definition A mannan-binding lectin serine protease 2 that is encoded in the genome of human.
Short Label hMASP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00187 (MASP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T250 Phosphorylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
Y388 Phosphorylation PhosphoSitePlus
Y394 Phosphorylation PhosphoSitePlus
Y401 Phosphorylation PhosphoSitePlus
T549 Phosphorylation PhosphoSitePlus
Y587 Phosphorylation PhosphoSitePlus
T599 Phosphorylation PhosphoSitePlus
Y602 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T262 I262 Biomuta DOID:184 / bone cancer [ icgc ] DOID:3371 / chondrosarcoma [ cosmic ]
Y587 N587 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]