iPTMnet Report for O00187 (MASP2)
Protein Information
| UniProt AC / UniProt ID | O00187 / MASP2_HUMAN |
| Protein Name | Mannan-binding lectin serine protease 2 precursor |
| Gene Name | Name: MASP2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O00187 |
| PRO Name | mannan-binding lectin serine protease 2 (human) |
| Definition | A mannan-binding lectin serine protease 2 that is encoded in the genome of human. |
| Short Label | hMASP2 |
| Category | organism-gene |
DAG ViewO00187 (MASP2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T262 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y388 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y394 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y401 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N547 | N-Glycosylation | score1 | GlyGen | 23090970 | ||
| T549 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y587 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T599 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y602 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T262 | I262 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| T549 | S549 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| Y587 | N587 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y602 | N602 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] |
