iPTMnet Report for O00159 (MYO1C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00159 / MYO1C_HUMAN
Protein Name Unconventional myosin-Ic
Gene Name Name: MYO1C
Organism Homo sapiens (Human)

PRO ID PR:O00159
DAG View
PRO Name unconventional myosin-Ic (human)
Definition A myosin-Ic that is encoded in the genome of human.
Short Label hMYO1C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00159 (MYO1C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S29 Phosphorylation PhosphoSitePlus
R33 Methylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
T150 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
S225 Phosphorylation IEDB 35494241
S263 Phosphorylation PhosphoSitePlus
C272 Methylation IEDB 31844290
K274 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
T348 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
K396 Acetylation IEDB 34357683
K404 Ubiquitination PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S410 Phosphorylation PhosphoSitePlus
T415 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
Y473 Phosphorylation PhosphoSitePlus
K486 Acetylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K512 Ubiquitination PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
K595 Ubiquitination PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
Y622 Phosphorylation PhosphoSitePlus
K632 Ubiquitination PhosphoSitePlus
K647 Acetylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
Y648 Phosphorylation PhosphoSitePlus
K667 Acetylation PhosphoSitePlus
K676 Ubiquitination PhosphoSitePlus
C679 Methylation IEDB 31844290
K704 Acetylation PhosphoSitePlus
K704 Ubiquitination PhosphoSitePlus
Y708 Phosphorylation PhosphoSitePlus
K721 Ubiquitination PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
C763 Methylation IEDB 31844290
T786 Phosphorylation PhosphoSitePlus
C802 S-Nitrosylation dbSNO 2212679, 22126794, 22178444
K858 Acetylation PhosphoSitePlus
S862 Phosphorylation PhosphoSitePlus
S864 Phosphorylation PhosphoSitePlus
K868 Methylation PhosphoSitePlus
K868 Ubiquitination PhosphoSitePlus
K874 Ubiquitination PhosphoSitePlus
K882 Ubiquitination PhosphoSitePlus
R894 Methylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
T943 Phosphorylation PhosphoSitePlus
K1005 Ubiquitination PhosphoSitePlus
S1015 Phosphorylation PhosphoSitePlus
T1034 Phosphorylation PhosphoSitePlus
T1038 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
K1047 Ubiquitination PhosphoSitePlus
K1049 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T41 Phosphorylation HPRD 20068231
T78 Phosphorylation HPRD 20068231
Y79 Phosphorylation HPRD 20068231
T147 Phosphorylation HPRD 20068231
T150 Phosphorylation HPRD 20068231
T348 Phosphorylation HPRD 20068231
S408 Phosphorylation HPRD 17081983, 18767875, 19691289, ...18669648, 19415658, 20068231
S410 Phosphorylation HPRD 20068231
T415 Phosphorylation HPRD 18452278
S432 Phosphorylation HPRD 18452278
Y440 Phosphorylation HPRD 18452278
T1038 Phosphorylation HPRD 20068231
T1046 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation HPRD 15302935
T43 Phosphorylation HPRD 20068231
Y44 Phosphorylation HPRD 20068231
T112 Phosphorylation HPRD 20068231
T115 Phosphorylation HPRD 20068231
T313 Phosphorylation HPRD 20068231
S373 Phosphorylation HPRD 17081983, 18767875, 19691289, ...18669648, 19415658, 20068231
S375 Phosphorylation HPRD 20068231
T380 Phosphorylation HPRD 18452278
S397 Phosphorylation HPRD 18452278
Y405 Phosphorylation HPRD 18452278
T1003 Phosphorylation HPRD 20068231
T1011 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y3 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
S10 Phosphorylation HPRD   PhosphoSitePlus 19691289
T22 Phosphorylation HPRD   PhosphoSitePlus 20068231
T59 Phosphorylation HPRD 20068231
Y60 Phosphorylation HPRD 20068231
T128 Phosphorylation HPRD 20068231
T131 Phosphorylation HPRD 20068231
T329 Phosphorylation HPRD 20068231
Y357 Phosphorylation PhosphoSitePlus
S389 Phosphorylation HPRD 17081983, 18767875, 19691289, ...18669648, 19415658, 20068231
S391 Phosphorylation HPRD 20068231
T396 Phosphorylation HPRD 18452278
S413 Phosphorylation HPRD 18452278
Y421 Phosphorylation HPRD 18452278
T1019 Phosphorylation HPRD 20068231
T1027 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 R3 Biomuta DOID:3571 / liver cancer [ cosmic ]
T115 N115 Biomuta DOID:1324 / lung cancer [ cosmic ]
T313 K313 Biomuta DOID:4159 / skin cancer [ cosmic ]
S397 R397 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]