Protein Information

Cytoscape View


UniProt AC / UniProt ID O00142 / KITM_HUMAN
Protein Name Thymidine kinase 2, mitochondrial precursor
Gene Name Name: TK2
Organism Homo sapiens (Human)

PRO ID PR:O00142
DAG View
PRO Name thymidine kinase 2, mitochondrial (human)
Definition A thymidine kinase 2, mitochondrial that is encoded in the genome of human.
Short Label hTK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00142 (TK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
Y181 Phosphorylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y190 F190 Biomuta DOID:1324 / lung cancer [ tcga ]