iPTMnet Report for O00139 (KIF2A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O00139 / KIF2A_HUMAN
Protein Name Kinesin-like protein KIF2A
Gene Name Name: KIF2A
Synonyms:KIF2,KNS2;
Organism Homo sapiens (Human)

PRO ID PR:O00139
DAG View
PRO Name kinesin-like protein KIF2A (human)
Definition A kinesin-like protein KIF2A that is encoded in the genome of human.
Short Label hKIF2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O00139 (KIF2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus   UniProt 19690332
T78 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19690332, 16565220
T97 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 23960144
S100 Phosphorylation PhosphoSitePlus   UniProt 23186163
K102 Acetylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S135 Phosphorylation Q6IQ55 (TTBK2) PhosphoSitePlus   RLIMS-P   UniProt 26323690, 23186163
S137 Phosphorylation PhosphoSitePlus
S140 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16565220
K147 Acetylation PhosphoSitePlus
K147 Methylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus   RLIMS-P 23960144
K161 Methylation PhosphoSitePlus
K169 Methylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
Y278 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K391 Methylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
S484 Phosphorylation IEDB   PhosphoSitePlus 27920218
K489 Ubiquitination PhosphoSitePlus
K508 Ubiquitination PhosphoSitePlus
R514 Methylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
C525 Methylation IEDB 31844290
T554 Phosphorylation P53350 (PLK1) PhosphoSitePlus   RLIMS-P 25660017
S585 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T609 Phosphorylation PhosphoSitePlus
S615 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
K696 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S100 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S75 Phosphorylation HPRD 20068231, 18452278
T78 Phosphorylation HPRD 16565220, 20058876, 20068231, ...18452278
S140 Phosphorylation HPRD 19651622, 19007248, 16565220
S695 Phosphorylation HPRD 19007248
Site PTM Type PTM Enzyme Score Source PMID
S75 Phosphorylation HPRD 20068231, 18452278
T78 Phosphorylation HPRD 20058876, 20068231, 18452278
S140 Phosphorylation HPRD 19651622, 19007248
S733 Phosphorylation HPRD 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S100 F100 Biomuta DOID:4159 / skin cancer [ cosmic ]
S107 L107 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S157 Y157 Biomuta DOID:363 / uterine cancer [ icgc ]
K452 I452 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S604 F604 Biomuta DOID:4159 / skin cancer [ cosmic ]
S683 Y683 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S683 C683 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S695 N695 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S733 N733 Biomuta DOID:4606 / bile duct cancer [ cosmic ]