iPTMnet Report for M0R2J8 (DCDC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID M0R2J8 / DCDC1_HUMAN
Protein Name Doublecortin domain-containing protein 1
Gene Name Name: DCDC1
Synonyms:DCDC5;
Organism Homo sapiens (Human)

PRO ID PR:M0R2J8
DAG View
PRO Name doublecortin domain-containing protein 1 (human)
Definition A doublecortin domain-containing protein 1 that is encoded in the genome of human.
Short Label hDCDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


M0R2J8 (DCDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K180 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
T705 Phosphorylation PhosphoSitePlus
K856 Acetylation PhosphoSitePlus
T965 Phosphorylation PhosphoSitePlus
S975 Phosphorylation PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus
S1058 Phosphorylation PhosphoSitePlus
T1235 Phosphorylation PhosphoSitePlus
S1515 Phosphorylation PhosphoSitePlus
T1517 Phosphorylation PhosphoSitePlus
S1518 Phosphorylation PhosphoSitePlus
S1520 Phosphorylation PhosphoSitePlus
T1600 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T317 K317 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S585 Y585 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T705 S705 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T965 M965 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S975 F975 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1052 R1052 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1052 N1052 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:263 / kidney cancer [ icgc ]
S1518 P1518 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]
S1520 T1520 Biomuta DOID:9256 / colorectal cancer [ cosmic ]