Protein Information

Cytoscape View


UniProt AC / UniProt ID E9PAV3 / NACAM_HUMAN
Protein Name Nascent polypeptide-associated complex subunit alpha, muscle-specific form
Gene Name Name: NACA
Organism Homo sapiens (Human)

PRO ID PR:E9PAV3
DAG View
PRO Name nascent polypeptide-associated complex subunit alpha, muscle-specific form isoforms h1/h2 (human)
Definition A nascent polypeptide-associated complex subunit alpha, muscle-specific form (human), isoforms h1 and h2.
Short Label hNACA/iso:muscle[h1/h2]
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


E9PAV3 (NACA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S271 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
T346 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus
S1411 Phosphorylation PhosphoSitePlus
S1512 Phosphorylation PhosphoSitePlus
S1906 Phosphorylation PhosphoSitePlus   Signor 15299025
S1906 Phosphorylation Q13418 (ILK) PhosphoSitePlus   Signor 15299025
K1929 Ubiquitination PhosphoSitePlus
K1931 Ubiquitination PhosphoSitePlus
K1941 Methylation PhosphoSitePlus
S1944 Phosphorylation PhosphoSitePlus
K1945 Ubiquitination PhosphoSitePlus
T1952 Phosphorylation PhosphoSitePlus
T1955 Phosphorylation PhosphoSitePlus
T1958 Phosphorylation PhosphoSitePlus
K1961 Ubiquitination PhosphoSitePlus
S1962 Phosphorylation PhosphoSitePlus
K1963 Sumoylation PhosphoSitePlus
K1963 Ubiquitination PhosphoSitePlus
K1971 Acetylation PhosphoSitePlus
K1971 Methylation PhosphoSitePlus
K1971 Ubiquitination PhosphoSitePlus
Y1975 Phosphorylation PhosphoSitePlus
K1976 Methylation PhosphoSitePlus
K1976 Ubiquitination PhosphoSitePlus
S1977 Phosphorylation PhosphoSitePlus
S1980 Phosphorylation PhosphoSitePlus
T1982 Phosphorylation PhosphoSitePlus
Y1983 Phosphorylation PhosphoSitePlus
K1990 Acetylation PhosphoSitePlus
K1990 Ubiquitination PhosphoSitePlus
S1995 Phosphorylation PhosphoSitePlus   UniProt 23186163
K2005 Acetylation PhosphoSitePlus   UniProt 19608861
K2005 Ubiquitination PhosphoSitePlus
K2007 Methylation PhosphoSitePlus
K2007 Ubiquitination PhosphoSitePlus
T2020 Phosphorylation PhosphoSitePlus
T2022 Phosphorylation PhosphoSitePlus   Signor 15005626
T2022 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 15005626
T2024 Phosphorylation PhosphoSitePlus   UniProt 18669648
S2029 Phosphorylation PhosphoSitePlus   UniProt 18691976, 18669648, 21406692, ...19690332
T2037 Phosphorylation PhosphoSitePlus
S2049 Phosphorylation PhosphoSitePlus   UniProt 17525332, 20068231
S2054 Phosphorylation PhosphoSitePlus   UniProt 18669648, 20068231
K2063 Ubiquitination PhosphoSitePlus
S2066 Phosphorylation PhosphoSitePlus   UniProt 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S1411 P1411 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S1962 Y1962 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y1975 C1975 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
Y1983 * Biomuta DOID:3571 / liver cancer [ icgc ]
T2024 P2024 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S2054 L2054 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]