iPTMnet Report for E7EW31 (PROB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID E7EW31 / PROB1_HUMAN
Protein Name Proline-rich basic protein 1
Gene Name Name: PROB1
Synonyms:C5orf65;
Organism Homo sapiens (Human)

PRO ID PR:E7EW31
DAG View
PRO Name proline-rich basic protein 1 (human)
Definition A proline-rich basic protein 1 that is encoded in the genome of human.
Short Label hPROB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


E7EW31 (PROB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S74 Phosphorylation PhosphoSitePlus
T234 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
T356 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
K729 Acetylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
S803 Phosphorylation PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
S855 Phosphorylation PhosphoSitePlus
T859 Phosphorylation PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
Y891 Phosphorylation PhosphoSitePlus
Y892 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S74 I74 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T253 M253 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S260 R260 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S260 G260 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S268 N268 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S411 L411 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S803 T803 Biomuta DOID:3571 / liver cancer [ cosmic ]
S865 T865 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y892 C892 Biomuta DOID:3571 / liver cancer [ cosmic ]