Protein Information

Cytoscape View

UniProt AC / UniProt ID C9JRZ8 / AK1BF_HUMAN
Protein Name Aldo-keto reductase family 1 member B15
Gene Name Name: AKR1B15
Organism Homo sapiens (Human)

DAG View
PRO Name aldo-keto reductase family 1 member B15 (human)
Definition An aldo-keto reductase family 1 member B15 that is encoded in the genome of human.
Short Label hAKR1B15
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

C9JRZ8 (AKR1B15) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R70 Methylation PhosphoSitePlus
K95 Acetylation PhosphoSitePlus
K117 Acetylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K179 Acetylation PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R70 L70 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K117 E117 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K179 N179 Biomuta DOID:2531 / hematologic cancer [ tcga ]
T288 N288 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]