iPTMnet Report for C9JH25 (PRRT4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID C9JH25 / PRRT4_HUMAN
Protein Name Proline-rich transmembrane protein 4 precursor
Gene Name Name: PRRT4
Organism Homo sapiens (Human)

PRO ID PR:C9JH25
DAG View
PRO Name proline-rich transmembrane protein 4 (human)
Definition A proline-rich transmembrane protein 4 that is encoded in the genome of human.
Short Label hPRRT4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


C9JH25 (PRRT4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S78 O-Glycosylation GlyGen 30459171
S139 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T143 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S206 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
C463 S-Nitrosylation dbSNO 26338901
S533 Phosphorylation PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus
K660 Ubiquitination PhosphoSitePlus
Y762 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S891 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S78 Y78 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S533 A533 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K660 E660 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S766 L766 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]