Protein Information

Cytoscape View


UniProt AC / UniProt ID B2RXH2 / KDM4E_HUMAN
Protein Name Lysine-specific demethylase 4E
Gene Name Name: KDM4E
Synonyms:KDM4DL;
Organism Homo sapiens (Human)

PRO ID PR:B2RXH2
DAG View
PRO Name lysine-specific demethylase 4E (human)
Definition A lysine-specific demethylase 4E that is encoded in the genome of human.
Short Label hKDM4E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


B2RXH2 (KDM4E) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y196 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S197 T197 Biomuta DOID:1319 / brain cancer [ cosmic ]
S452 G452 Biomuta DOID:3565 / meningioma [ cosmic ]