iPTMnet Report for A8K7I4 (CLCA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A8K7I4 / CLCA1_HUMAN
Protein Name Calcium-activated chloride channel regulator 1 precursor
Gene Name Name: CLCA1
Synonyms:CACC1;
Organism Homo sapiens (Human)

PRO ID PR:A8K7I4
DAG View
PRO Name calcium-activated chloride channel regulator 1 (human)
Definition A calcium-activated chloride channel regulator 1 that is encoded in the genome of human.
Short Label hCLCA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A8K7I4 (CLCA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y91 Phosphorylation PhosphoSitePlus
Y99 Phosphorylation PhosphoSitePlus
Y147 Phosphorylation PhosphoSitePlus
C187 S-Nitrosylation dbSNO 25040305
K208 Acetylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
C308 S-Nitrosylation dbSNO 25040305
S571 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
T578 Phosphorylation PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
Y661 Phosphorylation PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus
Y671 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y91 F91 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y99 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y219 N219 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T580 M580 Biomuta DOID:9256 / colorectal cancer [ cosmic ]