iPTMnet Report for A7MD48 (SRRM4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A7MD48 / SRRM4_HUMAN
Protein Name Serine/arginine repetitive matrix protein 4
Gene Name Name: SRRM4
Synonyms:KIAA1853;
Organism Homo sapiens (Human)

PRO ID PR:A7MD48
DAG View
PRO Name serine/arginine repetitive matrix protein 4 (human)
Definition A serine/arginine repetitive matrix protein 4 that is encoded in the genome of human.
Short Label hSRRM4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A7MD48 (SRRM4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T74 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S123 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
T228 Phosphorylation PhosphoSitePlus
T259 Phosphorylation PhosphoSitePlus
T269 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
T417 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
Y429 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S456 Phosphorylation HPRD   PhosphoSitePlus 17081983
Y457 Phosphorylation HPRD   PhosphoSitePlus 17081983
S458 Phosphorylation HPRD   PhosphoSitePlus 17081983
Y460 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
S527 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PhosphoSitePlus
S569 Phosphorylation IEDB 35494241
S570 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S579 Phosphorylation HPRD   PhosphoSitePlus 19651622
S591 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T74 I74 Biomuta DOID:1324 / lung cancer [ cosmic ]
S123 Y123 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S125 F125 Biomuta DOID:4159 / skin cancer [ cosmic ]
S125 C125 Biomuta DOID:3571 / liver cancer [ cosmic ]
S125 Y125 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T269 S269 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S301 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S390 F390 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y416 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S419 T419 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y429 F429 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K438 M438 Biomuta DOID:363 / uterine cancer [ icgc ]
Y460 D460 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S535 T535 Biomuta DOID:1324 / lung cancer [ cosmic ]
S542 R542 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S542 C542 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S579 C579 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]