iPTMnet Report for A7KAX9 (ARHGAP32)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A7KAX9 / RHG32_HUMAN
Protein Name Rho GTPase-activating protein 32
Gene Name Name: ARHGAP32
Synonyms:GRIT,KIAA0712,RICS;
Organism Homo sapiens (Human)

PRO ID PR:A7KAX9
DAG View
PRO Name Rho GTPase-activating protein 32 (human)
Definition A rho/Cdc42/Rac GTPase-activating protein RICS that is encoded in the genome of human.
Short Label hARHGAP32
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A7KAX9 (ARHGAP32) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation PhosphoSitePlus
T89 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S201 Phosphorylation PhosphoSitePlus
T514 Phosphorylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
S587 Phosphorylation PhosphoSitePlus
S591 Phosphorylation PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
Y621 Phosphorylation PhosphoSitePlus
S655 Phosphorylation PhosphoSitePlus
S659 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
K674 Acetylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
K688 Acetylation PhosphoSitePlus
S703 Phosphorylation PhosphoSitePlus
S706 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S709 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S732 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
S821 Phosphorylation PhosphoSitePlus
T845 Phosphorylation PhosphoSitePlus
S856 Phosphorylation PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus
Y889 Phosphorylation PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus   UniProt 23186163
S902 Phosphorylation PhosphoSitePlus
S904 Phosphorylation PhosphoSitePlus
T949 Phosphorylation PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y1069 Phosphorylation PhosphoSitePlus
Y1088 Phosphorylation PhosphoSitePlus
Y1097 Phosphorylation PhosphoSitePlus
S1181 Phosphorylation PhosphoSitePlus
S1203 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1215 Phosphorylation PhosphoSitePlus
Y1216 Phosphorylation PhosphoSitePlus
S1220 Phosphorylation PhosphoSitePlus
S1234 Phosphorylation PhosphoSitePlus
T1236 Phosphorylation PhosphoSitePlus
S1311 Phosphorylation PhosphoSitePlus
S1314 Phosphorylation PhosphoSitePlus
S1401 Phosphorylation PhosphoSitePlus
T1435 Phosphorylation PhosphoSitePlus
Y1440 Phosphorylation PhosphoSitePlus
T1445 Phosphorylation PhosphoSitePlus
T1449 Phosphorylation PhosphoSitePlus
Y1473 Phosphorylation PhosphoSitePlus
Y1520 Phosphorylation PhosphoSitePlus
R1523 Methylation PhosphoSitePlus
R1533 Methylation PhosphoSitePlus
Y1534 Phosphorylation PhosphoSitePlus
T1536 Phosphorylation PhosphoSitePlus
Y1537 Phosphorylation PhosphoSitePlus
Y1557 Phosphorylation PhosphoSitePlus
Y1577 Phosphorylation PhosphoSitePlus
T1579 Phosphorylation PhosphoSitePlus
S1585 Phosphorylation PhosphoSitePlus
S1596 Phosphorylation PhosphoSitePlus
S1600 Phosphorylation PhosphoSitePlus
Y1612 Phosphorylation PhosphoSitePlus
Y1632 Phosphorylation PhosphoSitePlus
T1635 Phosphorylation PhosphoSitePlus
Y1653 Phosphorylation PhosphoSitePlus
Y1660 Phosphorylation PhosphoSitePlus
Y1673 Phosphorylation PhosphoSitePlus
R1695 Methylation PhosphoSitePlus
K1699 Ubiquitination PhosphoSitePlus
S1700 Phosphorylation PhosphoSitePlus
Y1702 Phosphorylation PhosphoSitePlus
S1703 Phosphorylation PhosphoSitePlus
Y1704 Phosphorylation PhosphoSitePlus
Y1718 Phosphorylation PhosphoSitePlus
S1720 Phosphorylation PhosphoSitePlus
Y1739 Phosphorylation PhosphoSitePlus
Y1750 Phosphorylation PhosphoSitePlus
S1754 Phosphorylation PhosphoSitePlus
S1759 Phosphorylation PhosphoSitePlus
S1771 Phosphorylation PhosphoSitePlus
Y1773 Phosphorylation PhosphoSitePlus
T1777 Phosphorylation PhosphoSitePlus
Y1788 Phosphorylation PhosphoSitePlus
S1796 Phosphorylation PhosphoSitePlus
K1810 Ubiquitination PhosphoSitePlus
S1820 Phosphorylation PhosphoSitePlus
Y1828 Phosphorylation PhosphoSitePlus
S1854 Phosphorylation PhosphoSitePlus
S1873 Phosphorylation PhosphoSitePlus
S1884 Phosphorylation PhosphoSitePlus
Y1897 Phosphorylation PhosphoSitePlus
Y1920 Phosphorylation PhosphoSitePlus
S1923 Phosphorylation PhosphoSitePlus
Y1927 Phosphorylation PhosphoSitePlus
S1930 Phosphorylation PhosphoSitePlus
S1934 Phosphorylation PhosphoSitePlus
S1957 Phosphorylation PhosphoSitePlus
S1988 Phosphorylation PhosphoSitePlus
Y2005 Phosphorylation PhosphoSitePlus
Y2007 Phosphorylation PhosphoSitePlus
S2021 Phosphorylation PhosphoSitePlus
Y2023 Phosphorylation PhosphoSitePlus
Y2029 Phosphorylation PhosphoSitePlus
S2031 Phosphorylation PhosphoSitePlus
T2047 Phosphorylation PhosphoSitePlus
Y2048 Phosphorylation PhosphoSitePlus
T2060 Phosphorylation PhosphoSitePlus
Y2061 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S264 Phosphorylation HPRD 19413330
S357 Phosphorylation HPRD 19651622
S507 Phosphorylation HPRD 19413330
S522 Phosphorylation HPRD 19413330, 18452278
S543 Phosphorylation HPRD 19664994
T887 Phosphorylation HPRD 18691976
S1236 Phosphorylation HPRD 19413330
Y1680 Phosphorylation HPRD 17016520


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T89 N89 Biomuta DOID:363 / uterine cancer [ icgc ]
S201 Y201 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S264 Y264 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S613 Y613 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S682 I682 Biomuta DOID:3571 / liver cancer [ cosmic ]
S736 C736 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S902 L902 Biomuta DOID:4159 / skin cancer [ cosmic ]
S952 Y952 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S1220 N1220 Biomuta DOID:363 / uterine cancer [ icgc ]
S1234 F1234 Biomuta DOID:363 / uterine cancer [ icgc ]
T1435 I1435 Biomuta DOID:4159 / skin cancer [ cosmic ]
R1533 C1533 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y1612 H1612 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1612 C1612 Biomuta DOID:263 / kidney cancer [ icgc ]
K1699 T1699 Biomuta DOID:363 / uterine cancer [ icgc ]
Y1718 H1718 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1873 T1873 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1923 F1923 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1957 C1957 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]