iPTMnet Report for A6NMZ7 (COL6A6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A6NMZ7 / CO6A6_HUMAN
Protein Name Collagen alpha-6(VI) chain precursor
Gene Name Name: COL6A6
Organism Homo sapiens (Human)

PRO ID PR:A6NMZ7
DAG View
PRO Name collagen alpha-6(VI) chain (human)
Definition A collagen alpha-6(VI) chain that is encoded in the genome of human.
Short Label hCOL6A6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A6NMZ7 (COL6A6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N198 N-Glycosylation GlyGen   UniProt 19159218
Y247 Phosphorylation PhosphoSitePlus
N275 N-Glycosylation GlyGen   UniProt 29741879, 19159218
N288 N-Glycosylation GlyGen   UniProt 19159218
S321 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
N400 N-Glycosylation GlyGen 29741879
T412 Phosphorylation PhosphoSitePlus
T414 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
K472 Acetylation PhosphoSitePlus
T513 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
S629 Phosphorylation PhosphoSitePlus
S632 Phosphorylation PhosphoSitePlus
T730 Phosphorylation PhosphoSitePlus
N930 N-Glycosylation GlyGen   UniProt 29741879, 19159218
Y966 Phosphorylation PhosphoSitePlus
N988 N-Glycosylation GlyGen   UniProt 19159218
N1290 N-Glycosylation GlyGen   UniProt 19159218
S1369 Phosphorylation PhosphoSitePlus
S1489 Phosphorylation PhosphoSitePlus
S1492 Phosphorylation PhosphoSitePlus
S1728 Phosphorylation PhosphoSitePlus
S1730 Phosphorylation PhosphoSitePlus
T1731 Phosphorylation PhosphoSitePlus
Y1833 Phosphorylation PhosphoSitePlus
N2034 N-Glycosylation GlyGen 29741879
K2206 Ubiquitination PhosphoSitePlus
K2216 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y247 C247 Biomuta DOID:4159 / skin cancer [ cosmic ]
S321 N321 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T414 S414 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T414 A414 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K472 N472 Biomuta DOID:4159 / skin cancer [ cosmic ]
S632 R632 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y966 H966 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1369 R1369 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1489 Y1489 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S1492 N1492 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1728 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S1730 Y1730 Biomuta DOID:363 / uterine cancer [ icgc ]
K2216 N2216 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]