iPTMnet Report for A6NGG8 (PCARE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A6NGG8 / PCARE_HUMAN
Protein Name Photoreceptor cilium actin regulator
Gene Name Name: PCARE
Synonyms:C2orf71;
Organism Homo sapiens (Human)

PRO ID PR:A6NGG8
DAG View
PRO Name photoreceptor cilium actin regulator (human)
Definition A photoreceptor cilium actin regulator that is encoded in the genome of human.
Short Label hPCARE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A6NGG8 (PCARE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
Y273 Phosphorylation HPRD   PhosphoSitePlus 19901323
T274 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T369 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
T897 Phosphorylation PhosphoSitePlus
S1040 Phosphorylation PhosphoSitePlus
T1043 Phosphorylation PhosphoSitePlus
T1044 Phosphorylation PhosphoSitePlus
S1096 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S121 F121 Biomuta DOID:4159 / skin cancer [ cosmic ]
T153 M153 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T153 R153 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y273 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S276 C276 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1040 I1040 Biomuta DOID:4159 / skin cancer [ cosmic ]