iPTMnet Report for A6NC98 (CCDC88B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A6NC98 / CC88B_HUMAN
Protein Name Coiled-coil domain-containing protein 88B
Gene Name Name: CCDC88B
Synonyms:BRLZ;
Organism Homo sapiens (Human)

PRO ID PR:A6NC98
DAG View
PRO Name coiled-coil domain-containing protein 88B (human)
Definition A coiled-coil domain-containing protein 88B that is encoded in the genome of human.
Short Label hCCDC88B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A6NC98 (CCDC88B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus   UniProt 19690332
S596 Phosphorylation PhosphoSitePlus   UniProt 24275569
S597 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S839 Phosphorylation PhosphoSitePlus
C1228 Methylation IEDB 31844290
S1253 Phosphorylation PhosphoSitePlus
Y1277 Phosphorylation PhosphoSitePlus
S1345 Phosphorylation PhosphoSitePlus
S1370 Phosphorylation PhosphoSitePlus
S1379 Phosphorylation PhosphoSitePlus
S1397 Phosphorylation PhosphoSitePlus
S1405 Phosphorylation PhosphoSitePlus
S1406 Phosphorylation PhosphoSitePlus
S1408 Phosphorylation PhosphoSitePlus
S1410 Phosphorylation PhosphoSitePlus
T1471 Phosphorylation PhosphoSitePlus
S1475 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1405 Phosphorylation HPRD 20058876
S1406 Phosphorylation HPRD 20058876
S1408 Phosphorylation HPRD 20058876
Site PTM Type PTM Enzyme Score Source PMID
S988 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S489 Phosphorylation PhosphoSitePlus
R535 Methylation PhosphoSitePlus
R538 Methylation PhosphoSitePlus
R547 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S596 F596 Biomuta DOID:4159 / skin cancer [ cosmic ]
S596 Y596 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S597 F597 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S1253 I1253 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S1405 I1405 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1405 N1405 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]