iPTMnet Report for A4UGR9 (XIRP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A4UGR9 / XIRP2_HUMAN
Protein Name Xin actin-binding repeat-containing protein 2
Gene Name Name: XIRP2
Synonyms:CMYA3;
Organism Homo sapiens (Human)

PRO ID PR:A4UGR9
DAG View
PRO Name Xin actin-binding repeat-containing protein 2 (human)
Definition An Xin actin-binding repeat-containing protein 2 that is encoded in the genome of human.
Short Label hXIRP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A4UGR9 (XIRP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y51 Phosphorylation PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus
Y519 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
T963 Phosphorylation PhosphoSitePlus
T970 Phosphorylation PhosphoSitePlus
Y1137 Phosphorylation PhosphoSitePlus
S1265 Phosphorylation PhosphoSitePlus
T1283 Phosphorylation PhosphoSitePlus
T1285 Phosphorylation PhosphoSitePlus
T1303 Phosphorylation PhosphoSitePlus
T1461 Phosphorylation PhosphoSitePlus
K1603 Ubiquitination PhosphoSitePlus
S1629 Phosphorylation PhosphoSitePlus
T1631 Phosphorylation PhosphoSitePlus
T1652 Phosphorylation PhosphoSitePlus
S1672 Phosphorylation PhosphoSitePlus
S1674 Phosphorylation PhosphoSitePlus
K1722 Acetylation PhosphoSitePlus
K1729 Acetylation PhosphoSitePlus
K1766 Acetylation PhosphoSitePlus
K1771 Acetylation PhosphoSitePlus
R1796 Methylation PhosphoSitePlus
T1887 Phosphorylation PhosphoSitePlus
S1923 Phosphorylation PhosphoSitePlus
S1941 Phosphorylation PhosphoSitePlus
T1945 Phosphorylation PhosphoSitePlus
T2048 Phosphorylation PhosphoSitePlus
T2069 Phosphorylation PhosphoSitePlus
S2085 Phosphorylation PhosphoSitePlus
T2196 Phosphorylation PhosphoSitePlus
S2229 Phosphorylation PhosphoSitePlus
S2232 Phosphorylation PhosphoSitePlus
T2238 Phosphorylation PhosphoSitePlus
K2286 Acetylation PhosphoSitePlus
Y2361 Phosphorylation PhosphoSitePlus
K2727 Ubiquitination PhosphoSitePlus
K2739 Ubiquitination PhosphoSitePlus
S2754 O-Glycosylation GlyGen 30379171, 28411811, 29351928
Y2820 Phosphorylation PhosphoSitePlus
T2838 O-Glycosylation GlyGen 30379171, 28411811, 29351928
T2872 Phosphorylation PhosphoSitePlus
T2877 Phosphorylation PhosphoSitePlus
K2940 Ubiquitination PhosphoSitePlus
S2945 Phosphorylation PhosphoSitePlus
T2947 Phosphorylation PhosphoSitePlus
T2954 Phosphorylation PhosphoSitePlus
S2967 O-Glycosylation GlyGen 30379171, 28411811, 29351928
S2969 Phosphorylation PhosphoSitePlus
T2995 Phosphorylation PhosphoSitePlus
S2996 Phosphorylation PhosphoSitePlus
S2998 Phosphorylation PhosphoSitePlus
S3002 Phosphorylation PhosphoSitePlus
S3037 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S41 Phosphorylation PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
K175 Acetylation PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
Y771 Phosphorylation PhosphoSitePlus
S830 Phosphorylation PhosphoSitePlus
T840 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T3170 Phosphorylation HPRD 20166139
S3173 Phosphorylation HPRD 20166139
S3177 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S41 T41 Biomuta DOID:363 / uterine cancer [ icgc ]
Y90 C90 Biomuta DOID:363 / uterine cancer [ icgc ]
S459 Y459 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y519 C519 Biomuta DOID:4159 / skin cancer [ cosmic ]
S572 P572 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S830 I830 Biomuta DOID:363 / uterine cancer [ icgc ]
T840 I840 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T840 N840 Biomuta DOID:1324 / lung cancer [ cosmic ]
T963 N963 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1285 I1285 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1461 N1461 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1461 A1461 Biomuta DOID:363 / uterine cancer [ cosmic ]
K1603 E1603 Biomuta DOID:363 / uterine cancer [ cosmic ]
T1652 A1652 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1672 F1672 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S1674 N1674 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
K1771 T1771 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R1796 K1796 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T1887 M1887 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S1923 L1923 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1941 Y1941 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1945 I1945 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1945 N1945 Biomuta DOID:1324 / lung cancer [ cosmic ]
T2069 I2069 Biomuta DOID:4362 / cervical cancer [ cosmic ]
T2069 N2069 Biomuta DOID:363 / uterine cancer [ cosmic ]
S2229 F2229 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, tcga ]
S2232 C2232 Biomuta DOID:3571 / liver cancer [ cosmic ]
S2232 F2232 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
T2238 P2238 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K2286 N2286 Biomuta DOID:363 / uterine cancer [ cosmic ]
K2727 R2727 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K2739 N2739 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2754 F2754 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T2838 R2838 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T2838 I2838 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T2954 P2954 Biomuta DOID:1324 / lung cancer [ cosmic ]
S2967 P2967 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S2969 Y2969 Biomuta DOID:1324 / lung cancer [ cosmic ]
T2995 S2995 Biomuta DOID:1612 / breast cancer [ cosmic ]
S2996 F2996 Biomuta DOID:4159 / skin cancer [ cosmic ]
T3170 S3170 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]