iPTMnet Report for A3KMH1 (VWA8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A3KMH1 / VWA8_HUMAN
Protein Name von Willebrand factor A domain-containing protein 8 precursor
Gene Name Name: VWA8
Synonyms:KIAA0564;
Organism Homo sapiens (Human)

PRO ID PR:A3KMH1
DAG View
PRO Name von Willebrand factor A domain-containing protein 8 (human)
Definition A von Willebrand factor A domain-containing protein 8 that is encoded in the genome of human.
Short Label hVWA8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A3KMH1 (VWA8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
S226 O-Glycosylation GlyGen 30379171, 28510447
S226 Phosphorylation PhosphoSitePlus
Y267 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
K566 Acetylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus
Y1085 Phosphorylation PhosphoSitePlus
T1098 O-Glycosylation GlyGen 30379171, 28510447
S1235 Phosphorylation PhosphoSitePlus
S1249 Phosphorylation PhosphoSitePlus
S1400 Phosphorylation PhosphoSitePlus
Y1402 Phosphorylation PhosphoSitePlus
Y1440 Phosphorylation PhosphoSitePlus
K1584 Ubiquitination PhosphoSitePlus
K1683 Ubiquitination PhosphoSitePlus
S1707 Phosphorylation PhosphoSitePlus
Y1758 Phosphorylation PhosphoSitePlus
T1791 Phosphorylation PhosphoSitePlus
Y1837 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S226 C226 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y1085 C1085 Biomuta [ cosmic ]
S1400 L1400 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1400 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y1402 C1402 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]