iPTMnet Report for A2RUC4 (TYW5)
Protein Information
| UniProt AC / UniProt ID | A2RUC4 / TYW5_HUMAN |
| Protein Name | tRNA wybutosine-synthesizing protein 5 |
| Gene Name | Name: TYW5 Synonyms:C2orf60; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:A2RUC4 |
| PRO Name | tRNA wybutosine-synthesizing protein 5 (human) |
| Definition | A tRNA wybutosine-synthesizing protein 5 that is encoded in the genome of human. |
| Short Label | hTYW5 |
| Category | organism-gene |
DAG ViewA2RUC4 (TYW5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y48 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y187 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y189 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T285 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y293 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y48 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K260 | N260 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T285 | P285 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
