Protein Information

Cytoscape View


UniProt AC / UniProt ID A2RUB6 / CCD66_HUMAN
Protein Name Coiled-coil domain-containing protein 66
Gene Name Name: CCDC66
Organism Homo sapiens (Human)

PRO ID PR:A2RUB6
DAG View
PRO Name coiled-coil domain-containing protein 66 (human)
Definition A coiled-coil domain-containing protein 66 that is encoded in the genome of human.
Short Label hCCDC66
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A2RUB6 (CCDC66) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
T48 Phosphorylation PhosphoSitePlus
T50 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
T115 Phosphorylation PhosphoSitePlus   UniProt 18669648
K120 Acetylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus   UniProt 18669648
K132 Acetylation PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K269 Acetylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
T599 Phosphorylation PhosphoSitePlus
S603 Phosphorylation PhosphoSitePlus
K666 Acetylation PhosphoSitePlus
S669 Phosphorylation PhosphoSitePlus
K672 Acetylation PhosphoSitePlus
T691 Phosphorylation PhosphoSitePlus
Y719 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
S794 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
S797 Phosphorylation PhosphoSitePlus
T812 Phosphorylation PhosphoSitePlus
K913 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T81 Phosphorylation HPRD 18669648
T87 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T50 N50 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
T57 A57 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
K120 R120 Biomuta DOID:3571 / liver cancer [ tcga ]
K325 T325 Biomuta DOID:3571 / liver cancer [ tcga ]
K325 E325 Biomuta DOID:9256 / colorectal cancer [ tcga ]
T472 A472 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T599 A599 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S603 Y603 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T691 A691 Biomuta DOID:363 / uterine cancer [ icgc ]
T812 A812 Biomuta DOID:3070 / malignant glioma [ tcga ]
K913 T913 Biomuta DOID:0070003 / blastoma [ cosmic ]