iPTMnet Report for A2AJT9 (BCLAF3)
Protein Information
| UniProt AC / UniProt ID | A2AJT9 / BCLA3_HUMAN |
| Protein Name | BCLAF1 and THRAP3 family member 3 |
| Gene Name | Name: BCLAF3 Synonyms:CXorf23; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:A2AJT9 |
| PRO Name | BCLAF1 and THRAP3 family member 3 (human) |
| Definition | A BCLAF1 and THRAP3 family member 3 that is encoded in the genome of human. |
| Short Label | hBCLAF3 |
| Category | organism-gene |
A2AJT9 (BCLAF3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S15 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 18669648, 17081983 | ||
| S17 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 17081983 | ||
| S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S78 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| S80 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| S100 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K115 | Sumoylation | score1 | PhosphoSitePlus | |||
| S139 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 16565220 | ||
| S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K183 | Sumoylation | score1 | PhosphoSitePlus | |||
| S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S312 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K400 | Sumoylation | score1 | PhosphoSitePlus | |||
| S402 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S489 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K627 | Acetylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S15 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S17 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S73 | Phosphorylation | score0 | HPRD | 17081983 | ||
| Y74 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S78 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S80 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S15 | P15 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S15 | Y15 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S31 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S100 | L100 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| S100 | W100 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S162 | Y162 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S489 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S489 | L489 | Biomuta | DOID:363 / uterine cancer [ icgc, icgc ] DOID:1612 / breast cancer [ cosmic ] |
DAG View