iPTMnet Report for A2A5Z6 (Smurf2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A2A5Z6 / SMUF2_MOUSE
Protein Name E3 ubiquitin-protein ligase SMURF2
Gene Name Name: Smurf2
Organism Mus musculus (Mouse)

PRO ID PR:A2A5Z6
DAG View
PRO Name E3 ubiquitin-protein ligase SMURF2 (mouse)
Definition An E3 ubiquitin-protein ligase SMURF2 that is encoded in the genome of mouse.
Short Label mSMURF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A2A5Z6 (Smurf2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S44 Phosphorylation PhosphoSitePlus
T249 Phosphorylation PhosphoSitePlus   RLIMS-P 35304894
K345 Ubiquitination PhosphoSitePlus
S384 Phosphorylation RLIMS-P 33097595
K615 Ubiquitination PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation A2A5Z6 (Smurf2) S384 Q5DTM8 (Rnf20) unknown eFIP 33097595
Phosphorylation Q8BUN5 (Smad3) T179 A2A5Z6 (Smurf2) increased_association eFIP 22045334