Protein Information

Cytoscape View


UniProt AC / UniProt ID A2A3K4 / PTPC1_HUMAN
Protein Name Protein tyrosine phosphatase domain-containing protein 1
Gene Name Name: PTPDC1
Synonyms:PTP9Q22;
Organism Homo sapiens (Human)

PRO ID PR:A2A3K4
DAG View
PRO Name protein tyrosine phosphatase domain-containing protein 1 (human)
Definition A protein tyrosine phosphatase domain-containing protein 1 that is encoded in the genome of human.
Short Label hPTPDC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A2A3K4 (PTPDC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T34 Phosphorylation PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y393 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus   UniProt 23186163
T410 Phosphorylation PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
S438 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
T544 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus   UniProt 23186163
S553 Phosphorylation PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
K595 Ubiquitination PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus
T730 Phosphorylation PhosphoSitePlus
K732 Ubiquitination PhosphoSitePlus
T746 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S394 I394 Biomuta DOID:1324 / lung cancer [ tcga ]
S457 G457 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S547 I547 Biomuta DOID:3571 / liver cancer [ icgc ]
S553 C553 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]