iPTMnet Report for A2A2Y4 (FRMD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A2A2Y4 / FRMD3_HUMAN
Protein Name FERM domain-containing protein 3
Gene Name Name: FRMD3
Synonyms:EPB41L4O;
Organism Homo sapiens (Human)

PRO ID PR:A2A2Y4
DAG View
PRO Name FERM domain-containing protein 3 (human)
Definition A FERM domain-containing protein 3 that is encoded in the genome of human.
Short Label hFRMD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A2A2Y4 (FRMD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
K327 Methylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
T480 Phosphorylation PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S416 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S29 N29 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S313 P313 Biomuta DOID:1324 / lung cancer [ cosmic ]
S345 I345 Biomuta DOID:363 / uterine cancer [ icgc ]
T480 K480 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S482 L482 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]