iPTMnet Report for A1L0T0 (ILVBL)
Protein Information
| UniProt AC / UniProt ID | A1L0T0 / HACL2_HUMAN |
| Protein Name | 2-hydroxyacyl-CoA lyase 2 |
| Gene Name | Name: ILVBL Synonyms:AHAS,HACL2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:A1L0T0 |
| PRO Name | 2-hydroxyacyl-CoA lyase 2 (human) |
| Definition | A 2-hydroxyacyl-CoA lyase 2 that is encoded in the genome of human. |
| Short Label | hILVBL |
| Category | organism-gene |
DAG ViewA1L0T0 (ILVBL) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T114 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T121 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
| S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K227 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C276 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| T297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C354 | Methylation | score1 | IEDB | 31844290 | ||
| K389 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K429 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K577 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K599 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S629 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T114 | M114 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T121 | I121 | Biomuta | DOID:1319 / brain cancer [ icgc ] |
