iPTMnet Report for A1KXE4 (FAM168B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID A1KXE4 / F168B_HUMAN
Protein Name Myelin-associated neurite-outgrowth inhibitor
Gene Name Name: FAM168B
Synonyms:KIAA0280L,MANI;
Organism Homo sapiens (Human)

PRO ID PR:A1KXE4
DAG View
PRO Name myelin-associated neurite-outgrowth inhibitor (human)
Definition A myelin-associated neurite-outgrowth inhibitor that is encoded in the genome of human.
Short Label hFAM168B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


A1KXE4 (FAM168B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S6 Phosphorylation PhosphoSitePlus   UniProt 23186163
T57 Phosphorylation PhosphoSitePlus 18847512
T57 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
Y73 Phosphorylation PhosphoSitePlus
Y80 Phosphorylation PhosphoSitePlus
R88 Methylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 I6 Biomuta DOID:1324 / lung cancer [ cosmic ]
S10 P10 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R88 Q88 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ]