iPTMnet Report for A0AVT1 (UBA6)
Protein Information
UniProt AC / UniProt ID | A0AVT1 / UBA6_HUMAN |
Protein Name | Ubiquitin-like modifier-activating enzyme 6 |
Gene Name | Name: UBA6 Synonyms:MOP4,UBE1L2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:A0AVT1 |
PRO Name | ubiquitin-like modifier-activating enzyme 6 (human) |
Definition | A ubiquitin-like modifier-activating enzyme 6 that is encoded in the genome of human. |
Short Label | hUBA6 |
Category | organism-gene |
A0AVT1 (UBA6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330 | ||
S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y44 | Phosphorylation | score1 | PhosphoSitePlus | |||
T54 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
T146 | Phosphorylation | score1 | PhosphoSitePlus | |||
S149 | Phosphorylation | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
K238 | Ubiquitination | score1 | PhosphoSitePlus | |||
T241 | Phosphorylation | score1 | PhosphoSitePlus | |||
T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
S301 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
S317 | O-Glycosylation | score1 | GlyGen | 23301498, 28510447, 29351928 | ||
K342 | Ubiquitination | score1 | PhosphoSitePlus | |||
K488 | Ubiquitination | score1 | PhosphoSitePlus | |||
K490 | Ubiquitination | score1 | PhosphoSitePlus | |||
K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
K521 | Ubiquitination | score1 | PhosphoSitePlus | |||
K531 | Ubiquitination | score1 | PhosphoSitePlus | |||
K544 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K544 | Ubiquitination | score1 | PhosphoSitePlus | |||
K560 | Ubiquitination | score1 | PhosphoSitePlus | |||
K597 | Ubiquitination | score1 | PhosphoSitePlus | |||
K628 | Ubiquitination | score1 | PhosphoSitePlus | |||
T637 | Phosphorylation | score1 | PhosphoSitePlus | |||
K644 | Ubiquitination | score1 | PhosphoSitePlus | |||
K652 | Ubiquitination | score1 | PhosphoSitePlus | |||
K687 | Ubiquitination | score1 | PhosphoSitePlus | |||
K709 | Ubiquitination | score1 | PhosphoSitePlus | |||
C721 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K729 | Ubiquitination | score1 | PhosphoSitePlus | |||
S737 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K739 | Ubiquitination | score1 | PhosphoSitePlus | |||
S743 | Phosphorylation | score1 | PhosphoSitePlus | |||
K746 | Ubiquitination | score1 | PhosphoSitePlus | |||
K800 | Ubiquitination | score1 | PhosphoSitePlus | |||
K810 | Ubiquitination | score1 | PhosphoSitePlus | |||
K830 | Ubiquitination | score1 | PhosphoSitePlus | |||
K839 | Ubiquitination | score1 | PhosphoSitePlus | |||
K871 | Ubiquitination | score1 | PhosphoSitePlus | |||
K882 | Ubiquitination | score1 | PhosphoSitePlus | |||
K889 | Ubiquitination | score1 | PhosphoSitePlus | |||
S951 | Phosphorylation | score1 | PhosphoSitePlus | |||
K976 | Ubiquitination | score1 | PhosphoSitePlus | |||
K978 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y979 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y994 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1003 | Acetylation | score1 | PhosphoSitePlus | |||
K1003 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1011 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1051 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S36 | C36 | Biomuta | DOID:1324 / lung cancer [ cosmic, tcga ] | |
K115 | N115 | Biomuta | DOID:5041 / esophageal cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, tcga ] | |
T146 | K146 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
K169 | Q169 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc, tcga ] | |
T241 | A241 | Biomuta | DOID:3963 / thyroid carcinoma [ cosmic, icgc ] | |
S317 | R317 | Biomuta | DOID:2596 / larynx cancer [ cosmic ] | |
K597 | N597 | Biomuta | DOID:1324 / lung cancer [ tcga ] | |
S743 | C743 | Biomuta | DOID:11054 / urinary bladder cancer [ tcga ] | |
S817 | R817 | Biomuta | DOID:363 / uterine cancer [ tcga ] | |
K871 | T871 | Biomuta | DOID:1909 / melanoma [ cosmic ] | |
S951 | * | Biomuta | DOID:9256 / colorectal cancer [ icgc, tcga ] |