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Protein Ontology Report - mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1

PR:000044464 - http://purl.obolibrary.org/obo/PR_000044464
Ontology Information
PRO ID PR:000044464 Show OBO stanza / PAF
PRO name CEACAM1a-4L, signal peptide removed N-glycosylated and phosphorylated 1 (mouse)
Synonyms
PRO-short-label: mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1
PRO-proteoform-ftid: PRO_0000014563, Tyr-488/Tyr-515, MOD:00048|MOD:00160
PRO-proteoform-std: UniProtKB:P31809-1, 35-521, Tyr-488/Tyr-515, MOD:00048|MOD:00160
RELATED: Bgp D glycosylated and phosphorylated (mouse); Bgp1a/4L glycosylated and phosphorylated (mouse); Ceacam1a isoform Long glycosylated and phosphorylated (mouse); Ceacam1a/D1-4L glycosylated and phosphorylated (mouse)
Definition A carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form that is the signal cleavage product of isoform Long in mouse, includes at least one N-glycosylasparagine, and has been phosphorylated on Tyr-488 and Tyr-515 residues. UniProtKB:P31809-1, 35-521, Tyr-488/Tyr-515, MOD:00048|MOD:00160. [PMID:1648219, PMID:8896983, PMID:9047385, PMID:9867848, PRO:KRC, UniProtKB:P31809]
Comment Evidence=(ECO:0000250, based on PMID:1648219). Evidence=(ECO:0000250, based on UniProtKB:P31809). Evidence=(ECO:0000205, based on UniProtKB:P31809). Note: PMID:1648219 shows sequencing of mature N-terminus of Ceacam1 purified from Swiss Webster mice, but not specific to a sequence isoform; PMID:8896983 shows immunoblot showing native size of purified BgpA (Bgp1/4S) and BgpD (Bgp1/2S) and after N-glycanase treatment (Fig 2A); PMID:9867848 shows blots of a tyrosine phosphorylated Bgp1 form that migrates above the 116 kDa marker. Also show that tyrosine residues Tyr-488 and Tyr-515 in the C-terminus are required for the phosphorylation.
PRO Category organism-modification
Parent PR:000018399 carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form
Term Hierarchy Visualization DAG     OLS     Cytoscape

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Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044464
mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1
Tyr-488/Tyr-515, MOD:00048|MOD:00160
capable_of GO:0005515 protein binding with PR:P35235 mPTPN11 MGI:1326994, PMID:9867848
capable_of GO:0005515 protein binding with PR:P29351 mPTPN6 MGI:1326994, PMID:9867848
capable_of GO:0005515 protein binding with PR:P29351 mPTPN6 MGI:86453, PMID:9047385

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