[Term]
id: PR:000044464
name: CEACAM1a-4L, signal peptide removed N-glycosylated and phosphorylated 1 (mouse)
def: "A carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form that is the signal cleavage product of isoform Long in mouse, includes at least one N-glycosylasparagine, and has been phosphorylated on Tyr-488 and Tyr-515 residues. UniProtKB:P31809-1, 35-521, Tyr-488/Tyr-515, MOD:00048|MOD:00160." [PMID:1648219, PMID:8896983, PMID:9047385, PMID:9867848, PRO:KRC, UniProtKB:P31809]
comment: Category=organism-modification. Evidence=(ECO:0000250, based on PMID:1648219). Evidence=(ECO:0000250, based on UniProtKB:P31809). Evidence=(ECO:0000205, based on UniProtKB:P31809). Note: PMID:1648219 shows sequencing of mature N-terminus of Ceacam1 purified from Swiss Webster mice, but not specific to a sequence isoform; PMID:8896983 shows immunoblot showing native size of purified BgpA (Bgp1/4S) and BgpD (Bgp1/2S) and after N-glycanase treatment (Fig 2A); PMID:9867848 shows blots of a tyrosine phosphorylated Bgp1 form that migrates above the 116 kDa marker. Also show that tyrosine residues Tyr-488 and Tyr-515 in the C-terminus are required for the phosphorylation.
synonym: "mCEACAM1a/iso:4L/SigPep-/NGlycoPhos:1" EXACT PRO-short-label [PRO:DAN]
synonym: "Bgp D glycosylated and phosphorylated (mouse)" RELATED []
synonym: "Bgp1a/4L glycosylated and phosphorylated (mouse)" RELATED []
synonym: "PRO_0000014563, Tyr-488/Tyr-515, MOD:00048|MOD:00160" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "Ceacam1a/D1-4L glycosylated and phosphorylated (mouse)" RELATED []
synonym: "Ceacam1a isoform Long glycosylated and phosphorylated (mouse)" RELATED []
synonym: "UniProtKB:P31809-1, 35-521, Tyr-488/Tyr-515, MOD:00048|MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000018399 ! carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus