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Protein Ontology Report - CD247

PR:000001027 - http://purl.obolibrary.org/obo/PR_000001027
Ontology Information
PRO ID PR:000001027 Show OBO stanza / PAF
PRO name T-cell surface glycoprotein CD3
Synonyms
PRO-short-label: CD247
EXACT: T-cell receptor T3 eta chain; T-cell receptor T3 zeta chain
Gene-based: CD3Z; T3Z; TCRZ
Definition A protein that is a translation product of the human CD247 gene or a 1:1 ortholog thereof. It consists of an extracellular short N-terminal domain, a transmembrane domain, and an intracellular C-terminal domain with two to three copies of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). [PRO:CNA]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 2 organism-sequence 5
modification 5 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036628
hCD247/iso:CD3 zeta/Phos:1
located_in GO:0005886 plasma membrane PMID:9043947
participates_in GO:0050852 T cell receptor signaling pathway PMID:9043947
PR:000001027
CD247
has_part Pfam:PF02189 Immunoreceptor tyrosine-based activation motif PIRSF:PIRSF028738
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0050852 T cell receptor signaling pathway PR:000036628 hCD247/iso:CD3 zeta/Phos:1

PMID:9043947
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005886 plasma membrane PR:000036628 hCD247/iso:CD3 zeta/Phos:1

PMID:9043947

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