[Term]
id: PR:000001029
name: T-cell surface glycoprotein CD3 isoform CD3 zeta
def: "A T-cell surface glycoprotein CD3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24161-1 or a 1:1 ortholog thereof." [PMID:2150596, PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "CD3Z" EXACT []
synonym: "TCRZ" EXACT []
synonym: "CD-3-zeta" EXACT []
synonym: "CD247/iso:CD3 zeta" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000001027 ! T-cell surface glycoprotein CD3

[Term]
id: PR:000001028
name: T-cell surface glycoprotein CD3 isoform CD3 eta
def: "A T-cell surface glycoprotein CD3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24161-2 or a 1:1 ortholog thereof." [PMID:2150596, PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "CD-3-eta" EXACT []
synonym: "CD247/iso:CD3 eta" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000001027 ! T-cell surface glycoprotein CD3

[Term]
id: PR:000018329
name: T-cell surface glycoprotein CD3, signal peptide removed form
def: "A T-cell surface glycoprotein CD3 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "CD247/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000001027 ! T-cell surface glycoprotein CD3
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P20963-1
name: T-cell surface glycoprotein CD3 zeta chain (human)
def: "A T-cell surface glycoprotein CD3 isoform CD3 zeta that is encoded in the genome of human." [PRO:DNx, UniProtKB:P20963]
comment: Category=organism-sequence.
synonym: "hCD247/iso:CD3 zeta" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD3 zeta chain isoform CD-3-zeta (human)" EXACT [UniProtKB:P20963]
xref: UniProtKB:P20963-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001029 ! T-cell surface glycoprotein CD3 isoform CD3 zeta

[Term]
id: PR:P20963
name: T-cell surface glycoprotein CD3 (human)
def: "A T-cell surface glycoprotein CD3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P20963]
comment: Category=organism-gene.
synonym: "T3Z" RELATED Gene-based [UniProtKB:P20963]
synonym: "CD3Z" RELATED Gene-based [UniProtKB:P20963]
synonym: "TCRZ" RELATED Gene-based [UniProtKB:P20963]
synonym: "CD247" RELATED Gene-based [UniProtKB:P20963]
synonym: "hCD247" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell receptor T3 zeta chain (human)" EXACT [UniProtKB:P20963]
xref: UniProtKB:P20963
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000001027 ! T-cell surface glycoprotein CD3
relationship: has_gene_template HGNC:1677 ! CD247 (human)

[Term]
id: PR:000026560
name: T-cell surface glycoprotein CD3 isoform CD3 zeta, signal peptide removed form
def: "A T-cell surface glycoprotein CD3 isoform CD3 zeta that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "CD247/iso:CD3 zeta/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000001029 ! T-cell surface glycoprotein CD3 isoform CD3 zeta
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000003062
name: T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1
def: "A T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated form in which the phosphorylation occurs at the Tyr residues of the tyrosine-based activation motifs (TAMs, also known as Reth motifs), a 15-16 amino acid module containing two tyrosine residues." [PMID:2927501, PMID:7528772, PMID:8195151, PRO:CL]
comment: Category=modification.
synonym: "CD3 zeta activated" EXACT []
synonym: "CD3 zeta active form" EXACT []
synonym: "CD247/iso:CD3 zeta/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000003061 ! T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated form
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:000003061
name: T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated form
def: "A T-cell surface glycoprotein CD3 isoform CD3 zeta that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "CD247/iso:CD3 zeta/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000001029 ! T-cell surface glycoprotein CD3 isoform CD3 zeta

[Term]
id: PR:P24161
name: T-cell surface glycoprotein CD3 isoforms eta/zeta (mouse)
def: "A T-cell surface glycoprotein CD3 that is encoded in the genome of mouse." [OMA:P24161, PRO:DAN]
comment: Category=organism-gene.
synonym: "Cd3z" RELATED Gene-based [UniProtKB:P24161]
synonym: "Tcrz" RELATED Gene-based [UniProtKB:P24161]
synonym: "Cd247" RELATED Gene-based [UniProtKB:P24161]
synonym: "mCD247" EXACT PRO-short-label [PRO:DAN]
synonym: "CD247 (mouse)" EXACT [UniProtKB:P24161]
synonym: "T-cell receptor T3 zeta chain (mouse)" EXACT [UniProtKB:P24161]
xref: UniProtKB:P24161
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001027 ! T-cell surface glycoprotein CD3
relationship: has_gene_template MGI:88334 ! Cd247 (mouse)

[Term]
id: PR:P20963-2
name: T-cell surface glycoprotein CD3 eta chain (human)
def: "A T-cell surface glycoprotein CD3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20963-2." [PRO:DNx, UniProtKB:P20963]
comment: Category=organism-sequence.
synonym: "hCD247/iso:CD3 eta" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD3 zeta chain isoform CD-3-eta (human)" EXACT [UniProtKB:P20963]
xref: UniProtKB:P20963-2
is_a: PR:P20963 ! T-cell surface glycoprotein CD3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P20963-3
name: T-cell surface glycoprotein CD3 isoform 3 (human)
def: "A T-cell surface glycoprotein CD3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20963-3." [PRO:DNx, UniProtKB:P20963]
comment: Category=organism-sequence.
synonym: "hCD247/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P20963-3
is_a: PR:P20963 ! T-cell surface glycoprotein CD3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000026667
name: T-cell surface glycoprotein CD3 isoform CD3 eta, signal peptide removed form
def: "A T-cell surface glycoprotein CD3 isoform CD3 eta that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "CD247/iso:CD3 eta/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000001028 ! T-cell surface glycoprotein CD3 isoform CD3 eta
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000001027
name: T-cell surface glycoprotein CD3
def: "A protein that is a translation product of the human CD247 gene or a 1:1 ortholog thereof. It consists of an extracellular short N-terminal domain, a transmembrane domain, and an intracellular C-terminal domain with two to three copies of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM)." [PRO:CNA]
comment: Category=gene.
synonym: "T3Z" RELATED Gene-based []
synonym: "CD3Z" RELATED Gene-based []
synonym: "TCRZ" RELATED Gene-based []
synonym: "CD247" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell receptor T3 eta chain" EXACT []
synonym: "T-cell receptor T3 zeta chain" EXACT []
xref: PIRSF:PIRSF028738
is_a: PR:000000001 ! protein

[Term]
id: PR:P24161-1
name: T-cell surface glycoprotein CD3 zeta chain (mouse)
def: "A T-cell surface glycoprotein CD3 isoform CD3 zeta that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P24161]
comment: Category=organism-sequence.
synonym: "mCD247/iso:CD3 zeta" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD3 zeta chain isoform CD-3-zeta (mouse)" EXACT [UniProtKB:P24161]
xref: UniProtKB:P24161-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001029 ! T-cell surface glycoprotein CD3 isoform CD3 zeta

[Term]
id: PR:000036628
name: T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 (human)
def: "A T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1 in human." [PMID:9043947, PRO:CL]
comment: Category=organism-modification.
synonym: "hCD247/iso:CD3 zeta/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000003062 ! T-cell surface glycoprotein CD3 isoform CD3 zeta phosphorylated 1
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine

[Term]
id: PR:P24161-2
name: T-cell surface glycoprotein CD3 eta (mouse)
def: "A T-cell surface glycoprotein CD3 isoform CD3 eta that is encoded in the genome of mouse." [PRO:DAN, UniProtKB:P24161]
comment: Category=organism-sequence.
synonym: "mCD247/iso:CD3 eta" EXACT PRO-short-label [PRO:DNx]
synonym: "T-cell surface glycoprotein CD3 eta chain isoform CD-3-eta (mouse)" EXACT [UniProtKB:P24161]
xref: UniProtKB:P24161-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000001028 ! T-cell surface glycoprotein CD3 isoform CD3 eta