PRO ID |
PR:000000672
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/ PAF
|
PRO name |
cation channel sperm-associated auxiliary subunit beta |
Synonyms |
PRO-short-label: |
CATSPERB |
EXACT: |
CatSper-beta |
Gene-based: |
C14orf161 |
|
Definition |
A protein that is a translation product of the human CATSPERB gene or a 1:1 ortholog thereof. Members of this class are auxiliary proteins to the CatSper channel. They have four putative transmembrane-spanning domains. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel.
[PMID:17478420, PRO:CNA]
|
PRO Category |
gene |
Parent |
PR:000000001 protein |
Terms by PRO Category |
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Organism-Independent |
Organism-Specific |
Category |
Number of Terms |
Category |
Number of Terms |
gene
|
1 |
organism-gene
|
2 |
sequence
|
1 |
organism-sequence
|
3 |
modification
|
1 |
organism-modification
|
0 |
union
|
0 |
|
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