[Term]
id: PR:000000695
name: cation channel sperm-associated auxiliary subunit beta isoform 1
def: "A cation channel sperm-associated auxiliary subunit beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H7T0-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "CATSPERB/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000672 ! cation channel sperm-associated auxiliary subunit beta

[Term]
id: PR:000002588
name: cation channel sperm-associated auxiliary subunit beta isoform 1 unmodified form
def: "A cation channel sperm-associated auxiliary subunit beta isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "CATSPERB/iso:1/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000695 ! cation channel sperm-associated auxiliary subunit beta isoform 1
intersection_of: has_part PR:000021935 ! immature protein part
intersection_of: lacks_part PR:000025513 ! modified amino-acid residue
disjoint_from: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000000672
name: cation channel sperm-associated auxiliary subunit beta
def: "A protein that is a translation product of the human CATSPERB gene or a 1:1 ortholog thereof. Members of this class are auxiliary proteins to the CatSper channel. They have four putative transmembrane-spanning domains. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel." [PMID:17478420, PRO:CNA]
comment: Category=gene.
synonym: "CATSPERB" EXACT PRO-short-label [PRO:DNx]
synonym: "C14orf161" RELATED Gene-based []
synonym: "CatSper-beta" EXACT []
xref: PIRSF:PIRSF038543
is_a: PR:000000001 ! protein

[Term]
id: PR:A2RTF1
name: cation channel sperm-associated auxiliary subunit beta (mouse)
def: "A cation channel sperm-associated auxiliary subunit beta that is encoded in the genome of mouse." [OMA:A2RTF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Catsperb" RELATED Gene-based [UniProtKB:A2RTF1]
synonym: "mCATSPERB" EXACT PRO-short-label [PRO:DNx]
synonym: "CatSper-beta (mouse)" EXACT [UniProtKB:A2RTF1]
xref: UniProtKB:A2RTF1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000672 ! cation channel sperm-associated auxiliary subunit beta
relationship: has_gene_template MGI:2443988 ! Catsperb (mouse)

[Term]
id: PR:Q9H7T0
name: cation channel sperm-associated auxiliary subunit beta (human)
def: "A cation channel sperm-associated auxiliary subunit beta that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9H7T0]
comment: Category=organism-gene.
synonym: "CATSPERB" RELATED Gene-based [UniProtKB:Q9H7T0]
synonym: "C14orf161" RELATED Gene-based [UniProtKB:Q9H7T0]
synonym: "hCATSPERB" EXACT PRO-short-label [PRO:DNx]
synonym: "CatSper-beta (human)" EXACT [UniProtKB:Q9H7T0]
xref: UniProtKB:Q9H7T0
xref: Reactome:R-HSA-2534369 "PR:Q9H7T0 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000672 ! cation channel sperm-associated auxiliary subunit beta
relationship: has_gene_template HGNC:20500 ! CATSPERB (human)

[Term]
id: PR:Q9H7T0-2
name: cation channel sperm-associated auxiliary subunit beta isoform h2 (human)
def: "A cation channel sperm-associated auxiliary subunit beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H7T0-2." [PRO:DNx, UniProtKB:Q9H7T0]
comment: Category=organism-sequence.
synonym: "hCATSPERB/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H7T0-2
is_a: PR:Q9H7T0 ! cation channel sperm-associated auxiliary subunit beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:A2RTF1-1
name: cation channel sperm-associated auxiliary subunit beta isoform 1 (mouse)
def: "A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mCATSPERB/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:A2RTF1-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000695 ! cation channel sperm-associated auxiliary subunit beta isoform 1

[Term]
id: PR:Q9H7T0-1
name: cation channel sperm-associated auxiliary subunit beta isoform 1 (human)
def: "A cation channel sperm-associated auxiliary subunit beta isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hCATSPERB/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H7T0-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000695 ! cation channel sperm-associated auxiliary subunit beta isoform 1