Protein Ontology Report - lefty proteinPR:000000102 - http://purl.obolibrary.org/obo/PR_000000102 |
Ontology Information | |
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PRO ID | PR:000000102 Show OBO stanza / PAF |
PRO name | lefty protein |
Definition | A TGF-beta-like cystine-knot cytokine that is an antagonist of nodal signaling. The nodal and lefty genes form positive and negative regulatory loops that resemble the reaction-diffusion system. As a pair, these genes control various events of vertebrate embryonic patterning, including left-right specification and mesoderm formation. [PRO:CNA] |
PRO Category | family |
Parent | PR:000000008 TGF-beta-like cystine-knot cytokine |
Term Hierarchy Visualization | DAG OLS Cytoscape |
Related Cross References | |
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DB identifiers | PIRSF:PIRSF037402 |
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Functional Annotation
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