Protein Ontology Report - hSMURF1 PR:Q9HCE7 - http://purl.obolibrary.org/obo/PR_Q9HCE7

This page represents a class of proteins encompassing all the protein products of the SMURF1 gene in human .

Ontology Information
PRO ID	PR:Q9HCE7 Show OBO stanza / PAF
PRO name	E3 ubiquitin-protein ligase SMURF1 (human)
Synonyms	PRO-short-label: hSMURF1 EXACT: HECT-type E3 ubiquitin transferase SMURF1 (human); SMAD ubiquitination regulatory factor 1 (human); SMAD-specific E3 ubiquitin-protein ligase 1 (human) Gene-based: KIAA1625; SMURF1
Definition	An E3 ubiquitin-protein ligase SMURF1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q9HCE7]
PRO Category	organism-gene
Parent	PR:000000361 E3 ubiquitin-protein ligase SMURF1
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	HGNC:16807, Reactome:R-HSA-3004548, Reactome:R-HSA-975972, UniProtKB:Q9HCE7

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:Q9HCE7 hSMURF1 participates_in GO:0030514 negative regulation of BMP signaling pathway PMID:10458166 PR:Q9HCE7-2 hSMURF1/iso:Short capable_of GO:0004842 ubiquitin-protein transferase activity PMID:10458166 capable_of GO:0005515 protein binding PMID:11278251, PMID:16299379 located_in GO:0005622 intracellular anatomical structure PMID:10458166 participates_in GO:0030579 ubiquitin-dependent SMAD protein catabolic process PMID:12857866 participates_in GO:0006511 ubiquitin-dependent protein catabolic process PMID:10458166 participates_in GO:0006464 cellular protein modification process PMID:10458166 Biological Process GO Term Protein Forms & Complexes Evidence GO:0030514 negative regulation of BMP signaling pathway PR:Q9HCE7 hSMURF1 PMID:10458166 GO:0006511 ubiquitin-dependent protein catabolic process PR:Q9HCE7-2 hSMURF1/iso:Short PMID:10458166 GO:0030579 ubiquitin-dependent SMAD protein catabolic process PR:Q9HCE7-2 hSMURF1/iso:Short PMID:12857866 GO:0006464 cellular protein modification process PR:Q9HCE7-2 hSMURF1/iso:Short PMID:10458166 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005622 intracellular anatomical structure PR:Q9HCE7-2 hSMURF1/iso:Short PMID:10458166

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