[Term]
id: PR:Q9HCE7
name: E3 ubiquitin-protein ligase SMURF1 (human)
def: "An E3 ubiquitin-protein ligase SMURF1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9HCE7]
comment: Category=organism-gene.
synonym: "SMURF1" RELATED Gene-based [UniProtKB:Q9HCE7]
synonym: "hSMURF1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1625" RELATED Gene-based [UniProtKB:Q9HCE7]
synonym: "SMAD ubiquitination regulatory factor 1 (human)" EXACT [UniProtKB:Q9HCE7]
synonym: "HECT-type E3 ubiquitin transferase SMURF1 (human)" EXACT [UniProtKB:Q9HCE7]
synonym: "SMAD-specific E3 ubiquitin-protein ligase 1 (human)" EXACT [UniProtKB:Q9HCE7]
xref: UniProtKB:Q9HCE7
xref: Reactome:R-HSA-975972 "PR:Q9HCE7 located_in GO:0005829"
xref: Reactome:R-HSA-3004548 "PR:Q9HCE7 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000361 ! E3 ubiquitin-protein ligase SMURF1
relationship: has_gene_template HGNC:16807 ! SMURF1 (human)

[Term]
id: PR:Q9HCE7-1
name: E3 ubiquitin-protein ligase SMURF1 isoform Long (human)
def: "An E3 ubiquitin-protein ligase SMURF1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9HCE7-1." [PRO:DNx, UniProtKB:Q9HCE7]
comment: Category=organism-sequence.
synonym: "hSMURF1/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9HCE7-1
is_a: PR:Q9HCE7 ! E3 ubiquitin-protein ligase SMURF1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9HCE7-2
name: E3 ubiquitin-protein ligase SMURF1 isoform Short (human)
def: "An E3 ubiquitin-protein ligase SMURF1 isoform Short that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hSMURF1/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9HCE7-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000466 ! E3 ubiquitin-protein ligase SMURF1 isoform Short

[Term]
id: PR:000000361
name: E3 ubiquitin-protein ligase SMURF1
def: "A smad ubiquitination regulatory factor that is a translation product of the human SMURF1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "SMURF1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1625" RELATED Gene-based []
synonym: "SMAD ubiquitination regulatory factor 1" EXACT []
synonym: "smad ubiquitination regulatory factor 1" EXACT [PRO:CNA]
synonym: "HECT-type E3 ubiquitin transferase SMURF1" EXACT []
synonym: "SMAD-specific E3 ubiquitin-protein ligase 1" EXACT []
is_a: PR:000000127 ! smad ubiquitination regulatory factor