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Protein Ontology Report - hSIAH1

PR:Q8IUQ4 - http://purl.obolibrary.org/obo/PR_Q8IUQ4
This page represents a class of proteins encompassing all the protein products of the SIAH1 gene in human .
Ontology Information
PRO ID PR:Q8IUQ4 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase SIAH1 (human)
Synonyms
PRO-short-label: hSIAH1
Definition An E3 ubiquitin-protein ligase SIAH1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8IUQ4]
PRO Category organism-gene
Parent PR:000014860 E3 ubiquitin-protein ligase SIAH1
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 3
organism-modification 2
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025641
hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
has_function GO:0005515 protein binding increased relative to PR:000045369 hSIAH1/iso:1/UnPhos:1 with PR:Q69ZI1-1 mSH3RF1/iso:1 PMID:16230351
participates_in GO:0043525 positive regulation of neuron apoptotic process PMID:16230351
participates_in GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351
PR:000045369
hSIAH1/iso:1/UnPhos:1
Tyr-100/Tyr-126, PR:000026291
has_function GO:0005515 protein binding with PR:Q69ZI1 mSH3RF1 PMID:16230351
participates_in GO:0043525 positive regulation of neuron apoptotic process PMID:16230351
participates_in GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PMID:16230351
Molecular Function GO Term Protein Forms & Complexes Evidence
GO:0005515 protein binding PR:000025641 hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
increased relative to PR:000045369 hSIAH1/iso:1/UnPhos:1 with PR:Q69ZI1-1 mSH3RF1/iso:1
PMID:16230351
PR:000045369 hSIAH1/iso:1/UnPhos:1
Tyr-100/Tyr-126, PR:000026291
with PR:Q69ZI1 mSH3RF1
PMID:16230351
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade PR:000025641 hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
PMID:16230351
PR:000045369 hSIAH1/iso:1/UnPhos:1
Tyr-100/Tyr-126, PR:000026291
PMID:16230351
GO:0043525 positive regulation of neuron apoptotic process PR:000025641 hSIAH1/iso:1/Phos:1
Tyr-100/Tyr-126, MOD:00048
PMID:16230351
PR:000045369 hSIAH1/iso:1/UnPhos:1
Tyr-100/Tyr-126, PR:000026291
PMID:16230351

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