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Protein Ontology Report - hSMAD1

PR:Q15797 - http://purl.obolibrary.org/obo/PR_Q15797
This page represents a class of proteins encompassing all the protein products of the SMAD1 gene in human .
Ontology Information
PRO ID PR:Q15797 Show OBO stanza / PAF
PRO name mothers against decapentaplegic homolog 1 (human)
Synonyms
PRO-short-label: hSMAD1
EXACT: BSP-1 (human); JV4-1 (human); MAD homolog 1 (human); Mad-related protein 1 (human); SMAD 1 (human); SMAD family member 1 (human); Smad1 (human); mothers against DPP homolog 1 (human); transforming growth factor-beta-signaling protein 1 (human)
Gene-based: BSP1; MADH1; MADR1; SMAD1
Definition A smad1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q15797]
PRO Category organism-gene
Parent PR:000000363 smad1
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000026334
hSMAD1/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046 		capable_of GO:0046332 SMAD binding with PR:Q13485 hSMAD4 PMID:9136927
located_in GO:0005634 nucleus PMID:11509558, PMID:9759503
participates_in GO:0030509 BMP signaling pathway PMID:8653785
participates_in GO:0007165 signal transduction PMID:9759503
PR:Q15797-1
hSMAD1/iso:1
capable_of GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10708949
capable_of GO:0005515 protein binding with PR:Q7Z3T8 hZFYVE16 PMID:17356069
capable_of GO:0005102 signaling receptor binding PMID:9136927, PMID:9748228
located_in GO:0005737 cytoplasm PMID:11509558
participates_in GO:0030509 BMP signaling pathway PMID:8653785
participates_in GO:0007165 signal transduction PMID:8637600
PR:000036553
hSMAD1/iso:1/PhosUbiq:1
Ser-463/Ser-465, MOD:00046|MOD:01148 		participates_in GO:0030514 negative regulation of BMP signaling pathway PMID:12857866
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030514 negative regulation of BMP signaling pathway PR:000036553 hSMAD1/iso:1/PhosUbiq:1
Ser-463/Ser-465, MOD:00046|MOD:01148
PMID:12857866
GO:0030509 BMP signaling pathway PR:000026334 hSMAD1/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046
PMID:8653785
PR:Q15797-1 hSMAD1/iso:1

PMID:8653785
GO:0007165 signal transduction PR:000026334 hSMAD1/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046
PMID:9759503
PR:Q15797-1 hSMAD1/iso:1

PMID:8637600
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000026334 hSMAD1/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046
PMID:11509558, PMID:9759503
GO:0005737 cytoplasm PR:Q15797-1 hSMAD1/iso:1

PMID:11509558

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