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Protein Ontology Report - mRARB/iso:3

PR:P22605-3 - http://purl.obolibrary.org/obo/PR_P22605-3
Ontology Information
PRO ID PR:P22605-3 Show OBO stanza / PAF
PRO name retinoic acid receptor beta isoform 3 (mouse)
Synonyms
PRO-short-label: mRARB/iso:3
EXACT: RARB isoform Beta-2 (mouse)
Definition A retinoic acid receptor beta isoform 3 that is encoded in the genome of mouse. [PMID:1283441, PMID:1313565, PMID:1846599, PRO:AAA, PRO:KRC, UniProtKB:P22605]
Comment Note: PMID:1846599 provides cDNA evidence for isoforms beta-1, beta-2, and beta-3. PMID:1313565 shows cDNA evidence for isoforms beta-2 and beta-4. PMID:1283441 shows Western blot evidence with antibody against unique A region portion of beta-2 isoform shows that beta-2 isoform is expressed in embryonic mice.
PRO Category organism-sequence
Parent PR:000035618 retinoic acid receptor beta isoform 3
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P22605-3
mRARB/iso:3
capable_of GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI:3053708, PMID:1655807
participates_in GO:0008284 positive regulation of cell population proliferation MGI:81656, PMID:8681798
participates_in GO:0003406 retinal pigment epithelium development MGI:81656, PMID:8681798
participates_in GO:0060041 retina development in camera-type eye MGI:81656, PMID:8681798
participates_in GO:0043066 negative regulation of apoptotic process MGI:81656, PMID:8681798
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0043066 negative regulation of apoptotic process PR:P22605-3 mRARB/iso:3

MGI:81656, PMID:8681798
GO:0008284 positive regulation of cell population proliferation PR:P22605-3 mRARB/iso:3

MGI:81656, PMID:8681798
GO:0003406 retinal pigment epithelium development PR:P22605-3 mRARB/iso:3

MGI:81656, PMID:8681798
GO:0060041 retina development in camera-type eye PR:P22605-3 mRARB/iso:3

MGI:81656, PMID:8681798

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