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Protein Ontology Report - mEGR2

PR:P08152 - http://purl.obolibrary.org/obo/PR_P08152
This page represents a class of proteins encompassing all the protein products of the EGR2 gene in mouse .
Ontology Information
PRO ID PR:P08152 Show OBO stanza / PAF
PRO name E3 SUMO-protein ligase EGR2 (mouse)
Synonyms
PRO-short-label: mEGR2
EXACT: EGR-2 (mouse); early growth response protein 2 (mouse); zinc finger protein Krox-20 (mouse)
RELATED: Egr-2; Krox-20; Zfp-25
Definition An early growth response protein 2 that is encoded in the genome of mouse. [OMA:P08152, PRO:DNx]
PRO Category organism-gene
Parent PR:000003469 early growth response protein 2
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P08152-1
mEGR2/iso:Long
has_function GO:0003700 DNA-binding transcription factor activity PMID:8093858
has_function GO:0003677 DNA binding PMID:8093858, PMID:8895582
located_in GO:0005634 nucleus PMID:15282162
participates_in GO:0007622 rhythmic behavior PMID:8893031
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II PMID:8093858
PR:P08152-2
mEGR2/iso:Short
has_function GO:0005515 protein binding with PR:Q8C5D8-1 mPIAS2/iso:1 MGI:3629292, PMID:16675951
located_in GO:0005634 nucleus MGI:3629292, PMID:16675951
PR:P08152
mEGR2
participates_in GO:0021660 rhombomere 3 formation PMID:7903221
participates_in GO:0008045 motor neuron axon guidance PMID:9806922
participates_in GO:0021569 rhombomere 3 development PMID:9806922
participates_in GO:0042552 myelination PMID:10704452
participates_in GO:0042552 myelination PMID:16136673
participates_in GO:0006355 regulation of transcription, DNA-templated PMID:16136673
participates_in GO:0007622 rhythmic behavior PMID:8893031
participates_in GO:0021666 rhombomere 5 formation PMID:7903221
participates_in GO:0030278 regulation of ossification PMID:8565822
participates_in GO:0006355 regulation of transcription, DNA-templated PMID:10704452
participates_in GO:0014037 Schwann cell differentiation PMID:16136673
participates_in GO:0021612 facial nerve structural organization PMID:9806922
Molecular Function GO Term Protein Forms & Complexes Evidence
GO:0003700 DNA-binding transcription factor activity PR:P08152-1 mEGR2/iso:Long

PMID:8093858
GO:0003677 DNA binding PR:P08152-1 mEGR2/iso:Long

PMID:8093858, PMID:8895582
GO:0005515 protein binding PR:P08152-2 mEGR2/iso:Short

with PR:Q8C5D8-1 mPIAS2/iso:1
MGI:3629292, PMID:16675951
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007622 rhythmic behavior PR:P08152 mEGR2

PMID:8893031
PR:P08152-1 mEGR2/iso:Long

PMID:8893031
GO:0021666 rhombomere 5 formation PR:P08152 mEGR2

PMID:7903221
GO:0030278 regulation of ossification PR:P08152 mEGR2

PMID:8565822
GO:0006355 regulation of transcription, DNA-templated PR:P08152 mEGR2

PMID:16136673
PR:P08152 mEGR2

PMID:10704452
GO:0021569 rhombomere 3 development PR:P08152 mEGR2

PMID:9806922
GO:0021612 facial nerve structural organization PR:P08152 mEGR2

PMID:9806922
GO:0008045 motor neuron axon guidance PR:P08152 mEGR2

PMID:9806922
GO:0014037 Schwann cell differentiation PR:P08152 mEGR2

PMID:16136673
GO:0021660 rhombomere 3 formation PR:P08152 mEGR2

PMID:7903221
GO:0045944 positive regulation of transcription by RNA polymerase II PR:P08152-1 mEGR2/iso:Long

PMID:8093858
GO:0042552 myelination PR:P08152 mEGR2

PMID:10704452
PR:P08152 mEGR2

PMID:16136673
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:P08152-1 mEGR2/iso:Long

PMID:15282162
PR:P08152-2 mEGR2/iso:Short

MGI:3629292, PMID:16675951

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