Entry Report [PIR] - PR:000035663

Protein Ontology Report - hAURKB/Phos:1

PR:000035663 - http://purl.obolibrary.org/obo/PR_000035663

Protein Forms Annotations

Ontology Information

PRO ID

PR:000035663 Show OBO stanza / PAF

PRO name

aurora kinase B phosphorylated 1 (human)

Synonyms

PRO-short-label:	hAURKB/Phos:1
PRO-proteoform-std:	UniProtKB:Q96GD4, Ser-331, MOD:00046
RELATED:	hAURKB active form

Definition

An aurora kinase B phosphorylated 1 in human. This phosphorylated form is present during prometaphase, metaphase, and loss of tension on kinetochores (taxol). UniProtKB:Q96GD4, Ser-331, MOD:00046. [PMID:17276342, PMID:22024163, PMID:22024163, PMID:23321637, PRO:CNA, PRO:KER]

Comment

Kinase=("Chk1"; PR:O14757; Ser-331).Evidence=(ECO:0000006, based on PMID:22024163).

PRO Category

organism-modification

Parent

PR:000035662 aurora kinase B phosphorylated 1

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Centric View
GO Centric View

PRO Term	GO Annotation		Evidence
PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046	capable_of	GO:0004672 protein kinase activity increased relative to PR:000035661 hAURKB/PhosRes-	PMID:17276342, PMID:22024163
	capable_of	GO:0005515 protein binding with PR:Q9NQS7 hINCENP	PMID:22024163
	located_in	GO:0000776 kinetochore	PMID:22024163
	participates_in	GO:0007059 chromosome segregation increased relative to PR:000035661 hAURKB/PhosRes-	PMID:22024163
	participates_in	GO:0051310 metaphase plate congression increased relative to PR:000035661 hAURKB/PhosRes-	PMID:22024163
	participates_in	GO:0031577 spindle checkpoint signaling increased relative to PR:000035661 hAURKB/PhosRes-	PMID:22024163

Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0007059 chromosome segregation	PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 increased relative to PR:000035661 hAURKB/PhosRes-	PMID:22024163
GO:0051310 metaphase plate congression	PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 increased relative to PR:000035661 hAURKB/PhosRes-	PMID:22024163
GO:0031577 spindle checkpoint signaling	PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 increased relative to PR:000035661 hAURKB/PhosRes-	PMID:22024163

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0000776 kinetochore	PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046	PMID:22024163

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