back to PRO homepage

Protein Ontology Report - hCDC20/Phos:1

PR:000035371 - http://purl.obolibrary.org/obo/PR_000035371
Ontology Information
PRO ID PR:000035371 Show OBO stanza / PAF
PRO name cell division cycle protein 20 homolog phosphorylated 1 (human)
Synonyms
PRO-short-label: hCDC20/Phos:1
PRO-proteoform-std: UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047
RELATED: cdc20 phosphorylated (human)
Definition A cell division cycle protein 20 homolog phosphorylated 1 in human. This phosphorylated form occurs during mitotic splindle disruption (or with Nocodazole treatment) via BUB1 kinase activity. UniProtKB:Q12834, Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047. [PMID:15525512, PRO:KER]
Comment Kinase=("BUB1"; PR:O43683).
PRO Category organism-modification
Parent PR:000035370 cell division cycle protein 20 homolog phosphorylated 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035371
hCDC20/Phos:1
Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 		capable_of GO:0004842 ubiquitin-protein transferase activity decreased relative to PR:000035369 hCDC20/PhosRes- PMID:15525512
capable_of GO:0005515 protein binding with PR:O60566 hBUB1B PMID:15525512
capable_of GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512
located_in GO:0000776 kinetochore PMID:15525512
participates_in GO:0031577 spindle checkpoint signaling increased relative to PR:000035369 hCDC20/PhosRes- PMID:15525512
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0031577 spindle checkpoint signaling PR:000035371 hCDC20/Phos:1
Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047
increased relative to PR:000035369 hCDC20/PhosRes- 		PMID:15525512
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0000776 kinetochore PR:000035371 hCDC20/Phos:1
Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047
PMID:15525512

top