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Protein Ontology Report - hAKT1/iso:1/Phos:1

PR:000028994 - http://purl.obolibrary.org/obo/PR_000028994
Ontology Information
PRO ID PR:000028994 Show OBO stanza / PAF
PRO name RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 (human)
Synonyms
PRO-short-label: hAKT1/iso:1/Phos:1
PRO-proteoform-std: UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046
RELATED: Akt1 active form (human)
Definition A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1 in human. UniProtKB:P31749-1, Thr-308, MOD:00047|Ser-473, MOD:00046. [PMID:8978681, PRO:ALI]
Comment Kinase=("MAPKAPK2"; PR:000010165).
PRO Category organism-modification
Parent PR:000003103 RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000028994
hAKT1/iso:1/Phos:1
Thr-308, MOD:00047|Ser-473, MOD:00046 		capable_of GO:0005515 protein binding with PR:O14746-1 hTERT/iso:1 PMID:12586360
capable_of GO:0004672 protein kinase activity PMID:8978681
capable_of GO:0005515 protein binding with PR:P41279-1 hMAP3K8/iso:1 PMID:12138205
capable_of GO:0004674 protein serine/threonine kinase activity PMID:12138205
participates_in GO:0051092 positive regulation of NF-kappaB transcription factor activity PMID:12138205
participates_in GO:0032869 cellular response to insulin stimulus PMID:8978681
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0051092 positive regulation of NF-kappaB transcription factor activity PR:000028994 hAKT1/iso:1/Phos:1
Thr-308, MOD:00047|Ser-473, MOD:00046
PMID:12138205
GO:0032869 cellular response to insulin stimulus PR:000028994 hAKT1/iso:1/Phos:1
Thr-308, MOD:00047|Ser-473, MOD:00046
PMID:8978681

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