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Protein Ontology Report - hSMAD3/iso:1/Phos:1

PR:000026333 - http://purl.obolibrary.org/obo/PR_000026333
Ontology Information
PRO ID PR:000026333 Show OBO stanza / PAF
PRO name smad3 isoform 1 phosphorylated 1 (human)
Synonyms
PRO-short-label: hSMAD3/iso:1/Phos:1
PRO-proteoform-std: UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046
Definition A smad3 isoform 1 phosphorylated 1 in human. UniProtKB:P84022-1, Ser-423/Ser-425, MOD:00046. [PRO:DNx, UniProtKB:P84022]
PRO Category organism-modification
Parent PR:000000658 smad3 isoform 1 phosphorylated 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000026333
hSMAD3/iso:1/Phos:1
Ser-423/Ser-425, MOD:00046 		capable_of GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10823886, PMID:12943993
capable_of GO:0046332 SMAD binding with PR:Q13485 hSMAD4 PMID:15350224, PMID:9311995
capable_of GO:0008134 transcription factor binding PMID:15084259
located_in GO:0005634 nucleus PMID:10846168, PMID:15280432
part_of GO:0005667 transcription factor complex PMID:12374795
participates_in GO:0006366 transcription by RNA polymerase II PMID:10823886
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:8774881, PMID:9380693
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006366 transcription by RNA polymerase II PR:000026333 hSMAD3/iso:1/Phos:1
Ser-423/Ser-425, MOD:00046
PMID:10823886
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000026333 hSMAD3/iso:1/Phos:1
Ser-423/Ser-425, MOD:00046
PMID:8774881, PMID:9380693
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000026333 hSMAD3/iso:1/Phos:1
Ser-423/Ser-425, MOD:00046
PMID:10846168, PMID:15280432

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