back to PRO homepage

Protein Ontology Report - ESR1

PR:000007204 - http://purl.obolibrary.org/obo/PR_000007204
Ontology Information
PRO ID PR:000007204 Show OBO stanza / PAF
PRO name estrogen receptor
Synonyms
PRO-short-label: ESR1
EXACT: ER; ER-alpha; estradiol receptor; nuclear receptor subfamily 3 group A member 1
Gene-based: ESR; Estr; Estra; NR3A1
Definition A protein that is a translation product of the human ESR1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 6
sequence 1 organism-sequence 4
modification 6 organism-modification 7
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000027726
hESR1/iso:1/Phos:2
Tyr-52/Tyr-219, MOD:00048 		capable_of GO:0042803 protein homodimerization activity PMID:20101225
located_in GO:0005634 nucleus PMID:20101225
participates_in GO:0010628 positive regulation of gene expression PMID:20101225
PR:000027756
hESR1/iso:1/Ac:1
Lys-266/Lys-268, MOD:00064 		capable_of GO:0003677 DNA binding PMID:16497729
PR:000027724
hESR1/iso:1/Phos:1
Ser-167, MOD:00046 		participates_in GO:0045893 positive regulation of transcription, DNA-templated PMID:19940156
PR:000027776
hESR1/iso:1/Phos:4
Thr-311, MOD:00047 		located_in GO:0005634 nucleus PMID:12138194
participates_in GO:0010628 positive regulation of gene expression PMID:12138194
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0010628 positive regulation of gene expression PR:000027726 hESR1/iso:1/Phos:2
Tyr-52/Tyr-219, MOD:00048
PMID:20101225
PR:000027776 hESR1/iso:1/Phos:4
Thr-311, MOD:00047
PMID:12138194
GO:0045893 positive regulation of transcription, DNA-templated PR:000027724 hESR1/iso:1/Phos:1
Ser-167, MOD:00046
PMID:19940156
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000027726 hESR1/iso:1/Phos:2
Tyr-52/Tyr-219, MOD:00048
PMID:20101225
PR:000027776 hESR1/iso:1/Phos:4
Thr-311, MOD:00047
PMID:12138194

top