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Protein Ontology Report - CDC20

PR:000005188 - http://purl.obolibrary.org/obo/PR_000005188
Ontology Information
PRO ID PR:000005188 Show OBO stanza / PAF
PRO name cell division cycle protein 20 homolog
Synonyms
PRO-short-label: CDC20
EXACT: mmCdc20; p55CDC
Definition A protein that is a translation product of the human CDC20 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 6
sequence 1 organism-sequence 3
modification 5 organism-modification 7
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

CDC20 forms found in complexes
CDC20 Component Complexes
PR:Q12834 hCDC20 PR:000035575 BUB1B:CDC20 complex (human)
PR:Q12834 hCDC20 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human)
PR:Q6DFD4 frog-CDC20 PR:000035512 BUB1B:BUB3:MAD2:CDC20 complex (frog)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035369
hCDC20/PhosRes-
capable_of GO:0004842 ubiquitin-protein transferase activity PMID:15525512
capable_of GO:0005515 protein binding with PR:O60566 hBUB1B PMID:15525512
capable_of GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512
located_in GO:0000776 kinetochore PMID:15525512
participates_in GO:0031577 spindle checkpoint signaling PMID:15525512
PR:000035444
frog-CDC20/Phos:4
Ser-50, MOD:00046|Thr-64/Thr-68/Thr-79, MOD:00047 		capable_of GO:0005515 protein binding increased relative to PR:000035628 frog-CDC20/PhosRes- with PR:O60566 hBUB1B PMID:12855955
capable_of GO:0005515 protein binding increased relative to PR:000035628 frog-CDC20/PhosRes- with PR:P79935 frog-MAD2L1 PMID:12855955
participates_in GO:0031577 spindle checkpoint signaling increased relative to PR:000035628 frog-CDC20/PhosRes- PMID:12855955
PR:Q12834
hCDC20
capable_of GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:20624902
capable_of GO:0005515 protein binding with PR:O60566 hBUB1B PMID:11030144, PMID:20624902
PR:000035442
hCDC20/Phos:3
capable_of GO:0005515 protein binding decreased relative to PR:000035369 hCDC20/PhosRes- with PR:O60566 hBUB1B PMID:22566641
PR:000035371
hCDC20/Phos:1
Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 		capable_of GO:0004842 ubiquitin-protein transferase activity decreased relative to PR:000035369 hCDC20/PhosRes- PMID:15525512
capable_of GO:0005515 protein binding with PR:O60566 hBUB1B PMID:15525512
capable_of GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512
located_in GO:0000776 kinetochore PMID:15525512
participates_in GO:0031577 spindle checkpoint signaling increased relative to PR:000035369 hCDC20/PhosRes- PMID:15525512
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0031577 spindle checkpoint signaling PR:000035369 hCDC20/PhosRes-

PMID:15525512
PR:000035371 hCDC20/Phos:1
Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047
increased relative to PR:000035369 hCDC20/PhosRes- 		PMID:15525512
PR:000035444 frog-CDC20/Phos:4
Ser-50, MOD:00046|Thr-64/Thr-68/Thr-79, MOD:00047
increased relative to PR:000035628 frog-CDC20/PhosRes- 		PMID:12855955
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0000776 kinetochore PR:000035369 hCDC20/PhosRes-

PMID:15525512
PR:000035371 hCDC20/Phos:1
Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047
PMID:15525512

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